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Forschung und Lehre am Lehrstuhl für integrative Psychiatrie und Psychotherapie

Im Rahmen des Lehrstuhls erfolgt eine strukturierte und supervidierte  Ausbildung von Student*innen und Studenten der Universität Witten/Herdecke. Ziel ist eine fundierte und praxisnahe klinische Ausbildung im Fach Psychiatrie und Psychotherapie. Neben der klinischen Tätigkeit in einem der Bereiche unserer Abteilung erfolgt eine zusätzliche theoretische Weiterbildung im Rahmen unseres abteilungsinternen Weiterbildungscurriculums und durch klinische Lehrvisiten.

Unsere Student*innen haben dabei die Möglichkeit alle Facetten der ambulanten und stationären psychiatrischen Behandlung kennenzulernen.

Im Bereich der Forschung arbeiten wir an abteilungsspezifischen Themen der integrativen Psychiatrie und in Kooperationsprojekten mit externen Partnern. Für Interessierte psychologische und ärztliche Kolleg*innen besteht die Möglichkeit zur Erstellung von Masterarbeiten und/oder Promotionen oder Habilitationen.

Aktuelle Forschungsprojekte

Studie zum Thema "Lichttherapie gegen Winterdepression": Hier finden Sie alle Infos zu unserer aktuellen Studie.

Publikationen am Lehrstuhl

  1. Research Topic Embodying Tool Use: from Cognition to Neurorehabilitation. Müller HHO among other authors. Frontiers e-book. Dec 2020.
  2. Occurence of Post-Traumatic Stress Symptoms, Anxiety and Depression in the Acute Phase of Transient Ischemic Attack and Stroke. Müller HHO, Czwalinna K,  Wang R, Lücke C, Lam AP, Philipsen A, Gschossmann JM, Moeller S. Psychiatric Quarterly. 6 Dec 2020. doi.org/10.1007/s11126-020-09873-9.
  3. Letter to the editor regarding the article “Assessment for vagus nerve stimulation in patients with difficult-to-treat depression: A model from the newcastle regional affective disorders service (RADS)” vagus nerve stimulation (VNS) in patients with difficult-to-treat depression – long-term outcome is improved but who are the right candidates for VNS? Müller HHO, Moeller S. Journal of Affective Disorders Volume 281, 15 February 2021, Page 90.
  4. Suizidalität und Suizidprävention. Klimovitskaya E, Hentschel V, Müller H. Notaufnahme up2date 2020; 2: 1–16.
  5. Aggravation of symptom severity in adult attention-deficit/hyperactivity disorder by latent Toxoplasma gondii infection: A case-control study. Lam AP, De Sordi D, Müller HHO, Lam MC, Angelika Carl A, Kohse K, Philipsen A. Scientific Reports. Jul 2020.
  6. Safety profile of methylphenidate under long-term treatment in adult ADHD patients. Kis B, Lücke C, Abdel-Hamid M, Heßmann P, Graf E, Berger M, Matthies S, Borel P, Sobanski E, Rösler M, Retz W, Jacob C, Colla M, Huss M, Jans T, Tebartz van Elst L, Müller HHO, Philipsen A; for the Comparison of Methylphenidate and Psychotherapy in Adult ADHD Study (COMPAS) Consortium. Pharmacopsychiatry. Jun 2020.
  7. Consumption of Synthetic Cannabinoids in Adult Attention-Deficit/Hyperactivity Disorder: a Pilot Study. Lam AP, Moeller S, Speitling C, Lam MC, Philipsen A, Müller HHO. International Journal of Mental Health and Addiction. March 2020. doi.org/10.1007/s11469-020-00248-6.
  8. Physical exercise in attention deficit hyperactivity disorder – evidence and implications for the treatment of borderline personality disorder. Mehren A, Reichert M, Coghill D, Müller HHO, Braun N, Philipsen A. Borderline Personality Disorder and Emotion Dysregulation, (2020) 7:1.
  9. Kidney-transplant patients receiving living- or dead-donor organs have similar psychological outcomes (findings from the PI-KT study). Müller HHO, Lücke C, Englbrecht M, Wiesener MS, Siller T, Philipsen A, Eckardt KU, Kornhuber J, Maler JM. Mental Illness. Jan 2020.
  10. Exploring Self-Paced Embodiable Neurofeedback for Post-Stroke Motor Rehabilitation. Spychala N,  Debener S, Bongartz E, Müller HHO,  Thorne JD, Alexandra Philipsen A, Braun N* . Front. Hum. Neurosci. - Brain-Computer Interfaces. Dec 2019.
  11. Wechsel der antipsychotischen Therapie. Cariprazin: regrediente Symptomatik, Remission unerwünschter Wirkungen. Deutsches Ärzteblatt, Sonderdruck. 11/2019.
  12. Das quantitative Leistungsvermögen in der Begutachtung psychischer Störungen in der Frage der Erwerbsminderung nach § 43 SGB VI – Modell und praktisches Vorgehen. Quantitative assessment of the possible hours of work in psychiatric expert witness assessment - Model and practical procedure. Groemer TW, Käfferlein W, Kornhuber J, Capito ES, Jung M, Groemer KL, Müller HHO, Gaidzik P, Linden M. MedSach. Ausgabe 6/2019.
  13. Herbal detox – Benzodiazepine withdrawal treatment with the help of St. John's Wort? Moeller S, Sitter A, Darrelmann UG, Philipsen A,  Wang R, Olek A, Müller HHO. Asian J Psychiatr. 2019 Aug 23; 45:26-27.
  14. Rapid Titration Protocol - Experiences with a dynamic novel titration regime for vagus nerve stimulation in a group of depressive patients. Moeller S, Wang R, Aydin M, Lam AP, Sitter A, Grüter J, Philipsen A, Müller HHO. J Clin Neurosci. 2019 Aug 22.
  15. Patients with cervical intraepithelial neoplasms show different states of health-related quality of life and different coping styles depending on the choice of therapy: findings from the CIN Study. Klügel S, Lücke C, Mehren A, Malik E,  Philipsen A, Schild-Suhren M, Müller HHO. International Journal of Women's Health 2019:11 511–517.
  16. Effects of nature-based mindfulness training on resilience and psychiatric symptom load in professionals with high work-related stress levels: first findings from the Work Intervention through Nature study (WIN study). Lücke C, Braumandl S, Becker B, Moeller S, Custal C,  Philipsen A, Müller HHO. Mental Illness.  28 Nov 2019.
  17. Zwangsmaßnahmen in der Psychiatrie – Auch lege artis durchgeführt besteht ein Risiko für Komplikationen. Coercive Measures in Psychiatry – Even if Carried out lege artis Pose a Risk for Complications or Harm. Kersting XAK, Högenauer H, Lam AP, Janoschka J, Philipsen A, Müller HHO. Psychiat Prax 2019; 46: 1–3.
  18. Long-term Effects of Multimodal Treatment on Adult Attention-Deficit/Hyperactivity Disorder Symptoms Follow-up Analysis of the COMPAS Trial. Lam AP, Matthies S, Graf E, Colla M, Jacob C, Sobanski ,  Alm B, Rösler M, Retz W, Retz-Junginger P,  Kis B, Abdel-Hamid M, Müller HHO, Lücke C, Huss M, Jans T, Berger M, Tebartz van Elst L, Philipsen A, MD; for the Comparison of Methylphenidate and Psychotherapy in Adult ADHD Study (COMPAS) Consortium. JAMA Network Open. 2019;2(5):e194980.
  19. Ketamine – highly effective but many unanswered questions. Moeller S, Philipsen A, Müller HHO. The British Journal of Psychiatry (online). May 16; 2018.
  20. Acute Effects of Aerobic Exercise on Executive Function and Attention in Adult Patients with ADHD. Frontiers in Psychiatry, section Neuroimaging and Stimulation. Mehren A, Özyurt J, Lam AP, Brandes M, Müller HHO, Thiel CM, Philipsen A. Front. Psychiatry 2019.
  21. Hyperactivity/restlessness is associated with increased functional connectivity in adults with ADHD: a dimensional analysis of resting state fMRI. Sörös P , Hoxhaj E, Borel P, Sadohara C, Feige B, Matthies S, Müller HHO, Bachmann K, Schulze M, Philipsen A. BMC Psychiatry (2019) 19:43.
  22. Update on structured pain assessment for the documentation of diagnosis independent symptoms and signs associated with pain. Grömer TW, Atasever AT , Käfferlein W, Janoschka J ,  Moeller S,  Dohrenbusch R , Kappis R, Maihöfner C, Lücke C, Kornhuber J, Philipsen A, Müller HHO. Der Schmerz (Englisch), Jan 2019.
  23. Vagus Nerve Stimulation as an Adjunctive Neurostimulation Tool in Treatment-Resistant Depression. Moeller S, Lücke C, Heinen C, Bewernick BH, Aydin M, Lam AP, Grömer TW, Philipsen A, Müller HHO. J. Vis. Exp. (143), e58264, doi:10.3791/58264 (2019).
  24. Impact of bariatric surgery on neural food processing and cognition – an fMRI study" Schulze M, Sörös P, Vogel W, Münte T, Müller HHO, Philipsen A. BMJ Open, Oct. 2018.
  25. Versorgungsmodelle der Konsiliar-Liaison-Psychiatrie im Vergleich. Lücke C, Müller H. Psychopraxis. Neuropraxis. 2018.
  26. Association of Depression and Anxiety Disorders With Autoimmune Thyroiditis A Systematic Review and Meta-analysis-reply. Grömer TW, Siegmann EM, Müller HHO. JAMA Psychiatry. October 2018.
  27. Effects of mindfulness and psychoeducation on working memory in adult. ADHD: A randomised, controlled fMRI study. Bachmann K, Lam AP, Sörös P, Kanat M, Hoxhaje E, Matthies S, Feige B , Müller H, Özyurt J, Thiel CM, Philipsen A, Behaviour Research and Therapy, May 2018.
  28. Association of Depression and Anxiety Disorders With Autoimmune Thyroiditis A Systematic Review and Meta-analysis. Siegmann EM, Müller HHO, Luecke C, Alexandra Philipsen A, Kornhuber J, Grömer TW. JAMA Psychiatry. May 2, 2018.
  29. The senses of agency and ownership: a review. Braun N, Debener S, Spychala N,  Bongartz E, Sorös P,  Müller HHO,  Philipsen P. Front. Psychol.  April 2018.
  30. Vagus Nerve Stimulation (VNS) and Other Augmentation Strategies for Therapy-Resistant Depression (TRD): Review of the Evidence and Clinical Advice for Use. Müller HHO, Moeller S, Lücke C, Lam AP, Niclas Braun N, Philipsen A. Front. Neurosci. 10 April 2018.
  31. Off‑label prescription of psychiatric drugs by non‑psychiatrist physicians in three general hospitals in Germany. Lücke C, Gschossmann JM, Grömer TW, Moeller S, Schneider CE, Aikaterini Zikidi , Philipsen A, Müller HHO. Ann Gen Psychiatry (2018) 17:7.
  32. Mindfulness vs psychoeducation in adult ADHD: a randomized controlled trial. Hoxhaj E, Sadohara C, Borel P, D’Amelio R,  Sobanski E, Müller H, Feige B,  Matthies S, Philipsen A. European Archives of Psychiatry and Clinical Neuroscience 2018.
  33. Achieving stable remission with maintenance electroconvulsive therapy in a patient with treatment-resistant schizophrenia A case report. Moeller S, Kalkwarf N, Lücke C, Ortiz D, Jahn S, Först C, Braun N, Philipsen A, Müller HHO. Medicine (2017) 96:48.
  34. ADHS im Erwachsenenalter-Diagnostik und Therapie. Lam AP, Müller HHO, Philipsen A. Fortschr Neurol Psychatr 2017; 85:696-707.
  35. Concomitant psychiatric symptoms and impaired quality of life in women with cervical cancer: a critical review. Klügel S, Lücke C, Schild-Suhren M, Malik E, Philipsen A, Müller HHO. International Journal of Women`s Health. 2017:9.
  36. Inattention Predicts Increased Thickness of Left Occipital Cortex in Men with Attention-Deficit/Hyperactivity Disorder. Sörös P, Bachmann K, Lam AP, Kanat M, Hoxhaj E, Matthies S, Feige B, Müller HHO, Thiel C, Philipsen A. Front Psychiatry. 2017 Sep 13.
  37. Das AMDS-System zur Dokumentation von Schmerzbefunden. Grömer TW, Käfferlein W, Menger B, Dohrenbusch R, Kappis B · Maihöfner C, Kornhuber J, Philipsen A, Müller HHO. Der Schmerz. December 2017.
  38. Synthetic Cannabinoid Use in a Psychiatric Patient Population: A Pilot Study. Welter S, Lücke C, Lam AP, Custal C, Moeller S, Sörös P, Thiel CM, Philipsen A, Müller HHO. Eur Addict Res. August 2017.
  39. New psychotherapeutic approaches in adult ADHD – acknowledging biographical factors. Lücke C, Lam AP, Müller HH, Philipsen A. J Neurol Neuromed (2017) 2(7): 6-10.
  40. Efficacy and long-term tuning parameters of vagus nerve stimulation in longterm treated depressive patients. Müller HHO, Lücke C , Moeller S, Philipsen A, Sperling W. J Clin Neurosci (2017).
  41. Electroconvulsive therapy does not have negative effects on short-term memory function, as assessed using a bedside hand-held device. Müller HHO, Reike M, Grosse-Holz S, Röther M, Lücke C, Philipsen A, Kornhuber J, Grömer TW. Mental Illness 2017; 9:7093.
  42. Changing from somatic to psychiatric symptoms: a rare case report of Munchhausen’s syndrome. Hagen M, Faust B, Kunzelmann N, Tektas O, Kornhuber J, Müller HHO. Ment Illn. June 2017.
  43. Effective and underprescribed: What about clozapine? Müller HHO. Ment Illn. June 2017.
  44. Somatic Illness and Hospitalization as Triggers for Psychiatric Disorders of the Affective Spectrum: Results of a Large Study on Consultation-Liaison Psychiatry. Lücke C, Gschossmann JM, Bachmann K, Sörös P, Klügel S, Philipsen A, Müller HH. J Depress Anxiety 2017, 6:2.
  45. Cluster C personality accentuation in patients with takotsubo cardiomyopathy. Personality traits mark vulnerability. Müller HH, Sperling W, Kornhuber J. Psychiatria Danubina, 2017; Vol. 29, No. 1, pp 93.
  46. Early maladaptive schemas in adult patients with attention deficit hyperactivity disorder. Philipsen A, Lam AP, Breit S, Lücke C, Müller HH, Matthies S. Atten Defic Hyperact Disord. 2016 Dec 23.
  47. A comparison of two psychiatric service approaches: Findings from the Consultation vs. Liaison Psychiatry-Study. Lücke C, Gschossmann JM, Gschossmann J, Lam AP, Schneider CE, Philipsen A, Müller HH. BMC Psychiatry, December 2016.
  48. Ischemic stroke associated with the use of a Synthetic Cannabinoid (spice). Moeller S, Lücke C, Struffert T, Schwarze B, Gerner ST, Schwab S, Köhrmann M, Machold K, Philipsen A, Müller HH. Asian Journal of Psychiatry 25 (2017) 127–130.
  49. Differences in Intrusive Memory Experiences in Post-Traumatic Stress Disorder After Single, Re- And Prolonged Traumatization. Müller HH, Moeller S, Jenderek K, Stroebel A, Wiendieck K and Sperling W. Front. Psychol. 7:865. June 2016.
  50. Irreversible brain damage caused by methamphetamine. Moeller S, Huttner HB, Struffert S, Müller HHO. Alcohol. Drug Addict. 29 (2016) 39–41.
  51. Treatment escalation in patients not responding to pharmacotherapy, psychotherapy, and electro-convulsive therapy: experiences from a novel regimen using intravenous S-ketamine as add-on therapy in treatment-resistant depression. Kallmünzer B, Volbers B, Karthaus A, Tektas OY, Kornhuber J, Müller HH. J Neural Transm (Vienna). 2015 Dec 31.
  52. Depression, Anxiety, Resilience and Coping Pre and Post Kidney Transplantation - Initial Findings from the Psychiatric Impairments in Kidney Transplantation (PI-KT)-Study. Müller HH, Englbrecht M, Wiesener MS, Titze S, Heller K, Groemer TW, Schett G, Eckardt KU, Kornhuber J, Maler JM. PLoS One. 2015 Nov 11; eCollection 2015.
  53. The behavioral profile of spice and synthetic cannabinoids in humans. Müller HH, Kornhuber J, Sperling W. Brain Res Bull. 2015 Nov 5.
  54. “Herbal seizures” – atypical symptoms after ibogaine intoxication: a case report. Breuer L, Kasper BS, Schwarze B, Gschossmann JM, Kornhuber J, Müller HH. Journal of Medical Case Reports (2015) 9:243.
  55. Dialectical behaviour therapy in politics? Müller HH, Sperling W. The British Journal of Psychiatry (online). Aug 18; 2015.
  56. Innovative treatment based on historical roots. Müller HH, Linde O, Demling JH. Biol Psychiatry. 2015 Jul 8. 2015.
  57. Wiendieck K, Müller H, Buchfelder M, Sommer B. Mechanical stability of a novel screw design after repeated insertion: Can the double-thread screw serve as a back up? J Neurosurg Sci. 2015 Jul 22
  58. Prognostic influence of circadian rhythms on television viewers’ behavior: Is there a need for new programming? Müller HH, Moeller S, Ott B, Maihöfner C, Sperling W. Leisure Studies. 2015.
  59. Prognostic influence of witness/victim experiences and PTSD-specific symptoms on working and educational capacity: a comparison between two groups of individuals post-trauma. Müller HH, Moeller S, Hilger Y, Sperling W. Ann Gen Psychiatry. 2015 Feb 12, eCollection 2015.
  60. Depression and attempted suicide under pregabalin therapy. Kustermann A, Möbius C, Oberstein T, Müller HH, Kornhuber J. Ann Gen Psychiatry. 2014 Dec 4;13(1):37.
  61. c-MRI findings after crystal meth abuse. Möbius C, Kustermann A, Struffert T, Kornhuber J, Müller HH. J Addict Med. 2014 Sep-Oct;8(5):384-5.
  62. Psychische Störungen bei Nierenerkrankungen. Müller HH, Maler JM. Der Nierenarzt 1 /2014.
  63. Facilitative effects of VNS on the motor threshold: implications for its antidepressive mode of action? Müller HH, Reulbach U, Maler JM, Kornhuber J, Sperling W. J Neural Transm. 2013 Oct;120(10):1507-10. Epub 2013 Jun 5.
  64. The effects of stimulation parameters on clinical outcomes in patients with vagus nerve stimulation implants with major depression. Müller HH, Kornhuber J, Maler JM, Sperling W. J ECT. 2013 Sep;29(3):e40-2.
  65. iPad-assisted measurements of duration estimation in psychiatric patients and healthy control subjects. Preuschoff I, Müller HH, Sperling W, Biermann T, Bergner M, Kornhuber J, Groemer TW. PLoS One. 2013 May 2;8(5):e61295.
  66. Licht im Gehirn. Müller HH. Der Standard. April 2013.
  67. Media diseases of the never-sleeping brain: Was George Orwell right? Müller HH, Sperling W. OA Medical Hypothesis 2013 Apr 01;1(1):1.
  68. Resting motor threshold changes in vagus nerve stimulation-treated patients during on/off-stimulation conditions. Müller HH, Kornhuber J, Sperling W. Psychiatry Clin Neurosci. 2013 Jan;67(1):64-5.
  69. Agomelatine reduces craving in benzodiazepine addicts: a follow-up examination of three patients. Müller H, Seifert F, Maler JM, Kornhuber J, Sperling W. Singapore Med J. 2012 Nov;53(11):e228-30
  70. The renaissance of the collective unconscious? Müller HH, Sperling W. Acta Psychiatr Scand. 2012 Dec;126(6):480-1. Epub 2012 Oct 26.
  71. Correlation between homocysteine serum levels and the duration of seizures in patients treated with electroconvulsive therapy. Müller H, Maler JM, Kreil S, Rotter-Neubert A, Kornhuber J, Sperling W. J ECT. 2012 Sep;28(3):e37-8.
  72. Nude photography: abuse, obsession, delusion, and finally depression. Müller H, Knossalla F, Breuer L, Kornhuber J, Marquardt L. Am J Med. 2012 Aug;125(8):e3. Epub 2012 May 16.
  73. Global panic reaction II - a 7-step repetitive vicious circle. Sperling W, Müller H. Med Hypotheses. 2012 Jun;78(6):770-1. Epub 2012 Apr 6.
  74. Repetitive TMS Optimized by SPECT Control in Refractory Depression. Müller H, Biermann T, Seifert F, Maler JM, Kraus T, et al. (2012) J Depress Anxiety 1:113.
  75. Higher environmental temperature and global radiation are correlated with increasing suicidality--a localized data analysis. Müller H, Biermann T, Renk S, Reulbach U, Ströbel A, Kornhuber J, Sperling W. Chronobiol Int. 2011 Dec;28(10):949-57.
  76. Why not "double schizophrenia"? Sperling W, Müller H. Med Hypotheses. 2011 Nov;77(5):895-6. Epub 2011 Aug 30.
  77. Is tinnitus an acoasm? Sperling W, Mueller H, Kornhuber J, Biermann T. Med Hypotheses. 2011 Aug;77(2):216-9. Epub 2011 May 6.
  78. Persecution-induced reduction in earning capacity of Holocaust victims: influence of psychiatric and somatic aspects. Müller H, Seifert F, Asemann R, Schütz P, Maler JM, Sperling W. Psychopathology. 2011;44(4):225-9. Epub 2011 Apr 19.
  79. Nucleus lentiformis--a new model for psychiatry? Sperling W, Müller H. Med Hypotheses. 2011 May;76(5):720-2. Epub 2011 Mar 1.
  80. Long-term analysis of disability pensions in survivors of the Holocaust: somatic and psychiatric diagnoses. Biermann T, Sperling W, Müller H, Schütz P, Kornhuber J, Reulbach U. Fortschr Neurol Psychiatr. 2010 Dec;78(12):715-21. Epub 2010 Dec 6.
  81. Vagus-nerve stimulation is tolerated in a patient with cardiac AV-blocks. Müller H, Seifert F, Weigel D, Garlichs C, Asemann R, Flüh G, Kornhuber J, Sperling W. Prog Neuropsychopharmacol Biol Psychiatry. 2010 Jun 2.
  82. Psychological risk factors of kidney transplant patients. Müller H, Gwinner W, Haltenhof H, Kornhuber J, Maler JM. Kidney Int. 2010 May;77(9):833.
  83. Safety of vagus nerve stimulation in a patient with bipolar disorder and an implanted cardioverter-defibrillator. Müller H, Demling JH, Schütz P, Weigel D, Kornhuber J, Sperling W. Acta Neurol Scand. 2010 Apr;121(4):285-6; author reply 287-8. Epub 2010 Feb 17.
  84. Panic attack after spice abuse in a patient with ADHD. Müller H, Huttner HB, Köhrmann M, Wielopolski JE, Kornhuber J, Sperling W. Pharmacopsychiatry. 2010 Jun;43(4):152-3. Epub 2010 Feb 1.
  85. The synthetic cannabinoid Spice as a trigger for an acute exacerbation of cannabis induced recurrent psychotic episodes. Müller H, Sperling W, Köhrmann M, Huttner HB, Kornhuber J, Maler JM. Schizophr Res. 2010 May;118 (1-3):309-10. Epub 2010 Jan 8.
  86. Increased vagal modulation in atopic dermatitis. Boettger MK, Bär KJ, Dohrmann A, Müller H, Mertins L, Brockmeyer NH, Agelink MW. J Dermatol Sci. 2009 Jan;53(1):55-9. Epub 2008 Sep 13.

Ihr Ansprechpartner
Prof. Dr. med. Helge Müller IFAPA FRSM

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